The disease that was rejected once as “YUPIE flu” has genetic causes: study

Tired all the time? It may be in your DNA.

A New study It revealed amazing genetic differences in people with a devastating disease that causes severe fatigue, chronic pain and brain fog that can last for several months, years, or even contracts.

The researchers call the discovery a “vigil” call “that can finally transform the general perception of the incomprehensible situation, as soon as it is rejected as”A modern form of immunodeficiency insufficiency“I described”Yupie influenzaBy doctors, although their effective effects are often.

Chronic fatigue syndromeAlso known as ME/CFS, it is believed to affect 67 million people all over the world – including estimated estimates. 3.3 million Americans.

Until recently, it was not much known about the cause of the malfunction, which could turn a short distance into a large strait that leaves many patients with the symptoms that you do not relieve.

For years, doctors classified Me/CFS as a The psychological psychological issue Instead of physical disorder. But an increasing collection of research, including the latest genetic results, indicates a clear biological basis.

“I/CFS is a serious disease and now you know that the genetics of someone can balance whether it has been diagnosed with it,” Dr. Chris PontangA main investigator at Edinburgh University said in statement.

The study analyzed DNA samples from more than 15,500 European origin with me/CFS as part of DecodemeThe world’s largest data group on the disease.

Researchers found eight main areas of DNA where the differences were more common in ME/CFS patients compared to the general population.

Two of these DNA signals are linked to the body’s response to the infection, as they are in line with the patient’s repeated reports that the symptoms began after recovering from a contagious disease.

Another genetic mark overlaps with chronic pain – a common complaint between those suffering from Me/CFS.

“Since the DNA does not change with the appearance of Me/CFS, these results reflect the causes instead of the effects of Me/CFS,” the researchers wrote.

“These results are a pioneer,” said Sonia Chaudhry, CEO of the Charitable Society. Work for me Decodeme participating in simulation. “We have moved from knowing almost anything about me/CFS leads to setting clear goals for the research.”

While the researchers say the results are not yet ready to direct diagnosis or treatment, they provide vital evidence about the origins of the disease and can pave the way for future breakthroughs.

“We illuminate the laser light on eight accurate areas of DNA, so that very concentrated research can now be conducted,” Chaudre said. “We hope to attract this researchers, drug developers and financing that is proportional to Me/CFS – and speeds up the discovery of treatments.”

Currently, there is no diagnostic test, effective treatment or treatment for me/CFS, according to Disease control and prevention centers.

Instead, doctors usually focus on relieving symptoms through interventions such as medications, stretching and movement treatments, acupuncture, or massage.

They may also recommend lifestyle strategies such as speedIt is a way that helps me/CFS patients to manage their activity levels to reduce the frequency and intensity of setbacks while staying as active as possible.

This study is currently from Edinburgh University and has not yet been reviewed.

Decodeme team urges researchers all over the world to take advantage of their data set and launch new targeted studies on Me/CFS, especially on these eight newly defined genetic signals.